Pantoprazole sodium hydrate - Mixture of impurities D and F

CAS: 624742-53-6

Ref. 3D-ID57909

Product Information

• Name: Pantoprazole sodium hydrate - Mixture of impurities D and F
• Synonyms: 5- and 6-(Di-fluoromethoxy)-2-[(RS)-[(3,4-dimethoxypyridin-2-yl)methyl]sulphinyl]-1-methyl-1H-benzimidazole

Description

Pantoprazole sodium hydrate is a custom synthesis that is used as a drug product. The CAS number for this compound is 624742-53-6. This compound has the following impurities: D and F. Pantoprazole sodium hydrate has been shown to be metabolized in vitro by human liver microsomes to its metabolites, including the following: (1) pantoprazol acid, (2) 4-hydroxypantoprazol acid, (3) 4-hydroxyisoxazole acid, and (4) 5-(4-hydroxyphenyl)-2H-1,2-benzoxazin-3(4H)-one. The metabolite 4-hydroxypantoprazol acid has been found to be pharmacologically active in animal models of gastric ulceration and healing.

• Brand: Biosynth

Chemical properties

• Molecular weight: 397.4 g/mol
• Formula: C₁₇H₁₇F₂N₃O₄S
• Purity: Min. 95%
• Color/Form: Off-white to yellow powder.
• InChI: InChI=1S/C17H17F2N3O4S/c1-22-13-8-10(26-16(18)19)4-5-11(13)21-17(22)27(23)9-12-15(25-3)14(24-2)6-7-20-12/h4-8,16H,9H2,1-3H3
• InChI key: InChIKey=FYIXLAGYOWZQJO-UHFFFAOYSA-N
• SMILES: COc1ccnc(CS(=O)c2nc3ccc(OC(F)F)cc3n2C)c1OC