Diclofenac impurity B

CAS: 22121-58-0

Ref. 3D-ID72468

Product Information

• Name: Diclofenac impurity B
• Synonyms: 2-[(2,6-Dichlorophenyl)amino]benzaldehyde
• Brand: Biosynth
• Description: Diclofenac impurity B is a regulatory impurity in the drug Diclofenac, which is a nonsteroidal anti-inflammatory drug. Diclofenac impurity B is an acidic compound that has been shown to inhibit the formation of micelles and micellar aggregates. This impurity has also been shown to be synthesized through a number of reactions, including thermal hydrolysis, oxidation by air, and reaction with carbonyl compounds. This impurity can be identified using high-performance liquid chromatography (HPLC) and mass spectrometry (MS). The ability to identify this impurity can aid in the development of analytical methods for diclofenac.

Chemical properties

• Molecular weight: 266.12 g/mol
• Formula: C₁₃H₉Cl₂NO
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C13H9Cl2NO/c14-10-5-3-6-11(15)13(10)16-12-7-2-1-4-9(12)8-17/h1-8,16H
• InChI key: InChIKey=MILOIOYXRHLAAH-UHFFFAOYSA-N
• SMILES: O=Cc1ccccc1Nc1c(Cl)cccc1Cl