1-(2-Deoxy-a-D-ribofuranosyl)-5-azacytosine

CAS: 22432-95-7

Ref. 3D-ID74826

Product Information

• Name: 1-(2-Deoxy-a-D-ribofuranosyl)-5-azacytosine
• Synonyms: Decitabine impurity C4-Amino-1-(2-deoxy-?-D-erythro-pentofuranosyl)-s-triazin-2(1H)-onea-Decitabine, s-Triazin-2(1H)-one,4-amino-1-(2-deoxy-a-D-erythro-pentofuranosyl)- (8CI), Nsc 127717, a-Decitabine

Description

1-(2-Deoxy-a-D-ribofuranosyl)-5-azacytosine is a DNA methylation inhibitor that is used to treat cancer. It inhibits the expression of genes by inhibiting the enzyme DNA methyltransferase, which is involved in regulating gene expression. 1-(2-Deoxy-a-D-ribofuranosyl)-5-azacytosine has been shown to be effective against squamous cell carcinoma cells and has significant cytotoxicity against these cancer cells. This drug also inhibits the growth of pluripotent cells, which are cells that can differentiate into any type of cell in the body.

• Brand: Biosynth

Chemical properties

• Molecular weight: 228.21 g/mol
• Formula: C₈H₁₂N₄O₄
• Purity: Min. 95%
• InChI: InChI=1S/C8H12N4O4/c9-7-10-3-12(8(15)11-7)6-1-4(14)5(2-13)16-6/h3-6,13-14H,1-2H2,(H2,9,11,15)
• InChI key: InChIKey=XAUDJQYHKZQPEU-UHFFFAOYSA-N
• SMILES: Nc1ncn(C2CC(O)C(CO)O2)c(=O)n1