Product Information
YUKA1 is a protein that in humans is encoded by the YUK1 gene. It regulates cellular growth, differentiation and migration. YUKA1 has been shown to be overexpressed in breast cancer tissues, and has been shown to promote angiogenesis and tumor growth. This protein also interacts with the epidermal growth factor receptor (EGFR), which is a cell surface receptor tyrosine kinase involved in regulating cell proliferation, survival and motility. Yuka1 has been shown to bind histone H3 lysine 36 (H3K36) at specific regions of DNA called CpG islands. These regions are found near genes that are turned on or off by methylation, which can lead to changes in gene expression levels.
Chemical properties
Technical inquiry about: 3D-IDB99109 YUKA1
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