11-Fluoro desloratadine
CAS:
Ref. 3D-IF46257
1mg
341.00€
2mg
535.00€
5mg
1,036.00€
10mg
1,627.00€
25mg
2,112.00€
Product Information
Name:11-Fluoro desloratadine
Synonyms:
- Desloratadine impurity A8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
Brand:Biosynth
Description:11-Fluoro desloratadine is a metabolite of the antihistamine, loratadine. It has shown to be an analytical standard for HPLC, and impurity standard for pharmacopoeia. 11-Fluoro desloratadine is typically synthesized by reacting loratadine with fluorinating reagent such as N-fluorosuccinimide (NFSI) in the presence of a base catalyst such as sodium methoxide. 11-Fluoro desloratadine is also found in breast milk at concentrations of up to 1.2% of total loratadine concentration, which has been attributed to incomplete metabolism or passive transfer from mother to child.
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Chemical properties
Molecular weight:330.83 g/mol
Formula:C19H20N2ClF
Purity:Min. 95%
Color/Form:Powder
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