N-(((5R)-3-(3-Fluoro-4- (4-morpholinyl)phenyl)-2-oxo- 5-oxazolidinyl)methyl) acetamide

CAS: 872992-20-6

Ref. 3D-IF58037

Product Information

• Name: N-(((5R)-3-(3-Fluoro-4- (4-morpholinyl)phenyl)-2-oxo- 5-oxazolidinyl)methyl) acetamide
• Synonyms: (R)-Linezolid
• Brand: Biosynth
• Description: N-(((5R)-3-(3-Fluoro-4-(4-morpholinyl)phenyl)-2-oxo-5-oxazolidinyl)methyl)acetamide (LFMAPO) is an antibacterial agent that inhibits bacterial growth by binding to the active site of bacterial DNA gyrase. LFMAPO has a molecular weight of 552.2 Da and a log P value of 2.6. It was synthesized from acetamide, 3-fluoroaniline, and 4-(4-morpholinyl)benzaldehyde in 60% yield using techniques such as millimolar stoichiometry, electrophoresis method, binding constants, and molecular modeling study. The drug also has chiral properties with two stereocenters at carbons C1 and C5 that have been shown to be important for the activity of this compound against Gram positive bacteria.

Chemical properties

• Molecular weight: 337.35 g/mol
• Formula: C₁₆H₂₀FN₃O₄
• Purity: Min. 95%
• Color/Form: Powder