2-Hydroxy-2,2-bis(2-thienyl) acetic acid

CAS: 4746-63-8

Ref. 3D-IH41893

Product Information

• Name: 2-Hydroxy-2,2-bis(2-thienyl) acetic acid
• Synonyms: Di-2-thienylglycolic acidTiotropium Impurity A
• Brand: Biosynth
• Description: 2-Hydroxy-2,2-bis(2-thienyl) acetic acid is a long-acting bronchodilator that can be administered by inhalation. It has been used in the clinical development of medicines for the treatment of asthma and chronic obstructive pulmonary disease. 2-Hydroxy-2,2-bis(2-thienyl) acetic acid is chemically related to pyridinium compounds. It is a potent inhibitor of muscarinic receptors and has an anticholinergic profile similar to atropine. The safety profile of this drug seems to be favourable in humans with no major side effects reported so far.

Chemical properties

• Molecular weight: 240.3 g/mol
• Formula: C₁₀H₈O₃S₂
• Purity: Min. 95%
• Color/Form: Yellow Powder
• InChI: InChI=1S/C10H8O3S2/c11-9(12)10(13,7-3-1-5-14-7)8-4-2-6-15-8/h1-6,13H,(H,11,12)
• InChI key: InChIKey=FVEJUHUCFCAYRP-UHFFFAOYSA-N
• SMILES: O=C(O)C(O)(c1cccs1)c1cccs1