Product Information
- 1-O-[[6-(Trifluoromethoxy)-2-benzothiazolyl]amino]-b-D-glucopyranuronic acid
N-Hydroxy riluzole O-b-D-glucuronide is an analytical standard and drug development metabolite. It is a metabolite of the anti-convulsant agent riluzole, which is used in the treatment of amyotrophic lateral sclerosis (ALS). Riluzole is converted to N-hydroxyl riluzole O-b-D-glucuronide in the liver by UDP glucuronosyltransferase. N-Hydroxyl riluzole O-b-D-glucuronide has been shown to block protein synthesis in rat kidney cells. It also blocks the conversion of amino acid tyrosine to dopa in dopaminergic neurons, and inhibits dopamine uptake into synaptosomes.
Chemical properties
Technical inquiry about: 3D-IH59730 N-Hydroxy riluzole O-b-D-glucuronide
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