3-Fluoro-5-(morpholin-4-yl)aniline

CAS: 258864-18-5

Ref. 3D-IKA86418

Product Information

• Name: 3-Fluoro-5-(morpholin-4-yl)aniline
• Brand: Biosynth
• Description: 3-Fluoro-5-(morpholin-4-yl)aniline is a synthetic compound that has been shown to inhibit the growth of bacteria by binding to the enzyme dihydropteroate synthase. This drug inhibits bacterial growth by preventing the formation of folic acid, which is essential for DNA synthesis. 3-Fluoro-5-(morpholin-4-yl)aniline has also been shown to be selective against other enzymes in the folate pathway, such as thymidylate synthase and glycinamide ribonucleotide formyltransferase. Theoretical studies suggest that 3-fluoro-5-(morpholin-4-yl)aniline binds to the substrate binding site on dihydropteroate synthase and sterically hinders access to substrates in this region of the enzyme. Density functional theory calculations show that this compound binds more tightly than a number of natural products. Intramolecular

Chemical properties

• Molecular weight: 196.22 g/mol
• Formula: C₁₀H₁₃FN₂O
• Purity: Min. 95%
• Color/Form: Powder