HC-067047
CAS: 883031-03-6
Ref. 3D-IKB03103
| 1mg | 172.00 € | ||
| 5mg | 201.00 € | ||
| 10mg | 310.00 € | ||
| 25mg | 453.00 € | ||
| 50mg | 646.00 € |
Product Information
HC-067047 is an experimental drug that has been shown to decrease the intracellular Ca2+ concentration in various cell types, including neurons. This agent also inhibits the influx of Ca2+ ions through voltage-gated channels and blocks the release of Ca2+ from intracellular stores. HC-067047 is being investigated for chronic cough as it has been shown to reduce this symptom in a guinea pig model of asthma. In vitro studies have shown that HC-067047 is not active against protozoa or bacteria but does inhibit the growth of tumor cells. The mechanism of action for HC-067047 is not fully elucidated, but it may act by inhibiting ion transport proteins such as TRPV4, Toll-like receptor, or Ryanodine receptor. HC-067047 has also been found to increase MMP9 activity and inhibit production of cytokines such as IL-6 and TNFα.
Chemical properties
Technical inquiry about: 3D-IKB03103 HC-067047
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