Losartan imidazo[1,5-b]isoquinoline impurity

CAS: 165276-38-0

Ref. 3D-IL24943

Product Information

• Name: Losartan imidazo[1,5-b]isoquinoline impurity
• Synonyms: 3-Butyl-1-chloro-5,10-dihydro-8-[2-(2H-tetrazol-5-yl)phenyl]-imidazo[1,5-b]isoquinoline
• Brand: Biosynth
• Description: Losartan is a drug product that belongs to the class of losartan impurity. It is an impurity standard for research and development, as well as a custom synthesis. Losartan is also used in the synthesis of other drugs, such as losartan potassium, which is classified as a niche compound. Losartan impurity has been shown to be metabolized by several enzymes including CYP2C9 and CYP3A4. The metabolite identified from this study was N-desmethyl losartan.

Chemical properties

• Molecular weight: 404.9 g/mol
• Formula: C₂₂H₂₁ClN₆
• Purity: Min. 95%
• InChI: InChI=1S/C22H21ClN6/c1-2-3-8-20-24-21(23)19-12-16-11-14(9-10-15(16)13-29(19)20)17-6-4-5-7-18(17)22-25-27-28-26-22/h4-7,9-11H,2-3,8,12-13H2,1H3,(H,25,26,27,28)
• InChI key: InChIKey=RSKIKNQMNCWQMT-UHFFFAOYSA-N
• SMILES: CCCCc1nc(Cl)c2n1Cc1ccc(-c3ccccc3-c3nn[nH]n3)cc1C2