N2-Losartanyl-losartan

CAS: 230971-72-9

Ref. 3D-IL24948

Product Information

• Name: N2-Losartanyl-losartan
• Synonyms: 2-Butyl-1-[[2'-[2-[[2-butyl-4-chloro-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazol-5-yl]methyl]-2H-tetrazol-5-yl ][1,1'-biphenyl]-4-yl]methyl]-4-chloro-1H-imidazole-5-methanol
• Brand: Biosynth
• Description: N2-Losartanyl-losartan is a drug product that has a CAS number of 230971-72-9. This product is an analytical standard for the metabolites of losartan, which is a drug used to treat high blood pressure and heart failure. Metabolism studies have shown that losartan is metabolized by hydroxylation, glucuronidation, and oxidation by cytochrome P450 enzymes. Losartan has also been found to be converted into an active metabolite in the body, which is called N2-hydroxy-losartan. It has been shown to be more potent than losartan at blocking angiotensin II receptors.

Chemical properties

• Molecular weight: 827.81 g/mol
• Formula: C₄₄H₄₄Cl₂N₁₂O
• Purity: Min. 95%