Lansoprazole sulfone

CAS: 131926-99-3

Ref. 3D-IL32158

Product Information

• Name: Lansoprazole sulfone
• Synonyms: Lansoprazole impurity B2-[[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfonyl]-1H-benzimidazole, Ag 1813, Lansoprazole SulfoneDiscontinued See: L175026, 2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methyl]sulphonyl]-1H-benzimidazole

Description

Lansoprazole sulfone is a prodrug of lansoprazole that is metabolized by cytochrome P450 enzymes. Lansoprazole sulfone has a pharmacokinetic profile similar to the parent drug and is used to treat gastroesophageal reflux disease in adults. The human pharmacokinetics of lansoprazole sulfone have been determined using recombinant cytochrome P450 enzymes and analytical methods. Lansoprazole sulfone has been shown to be effective against gastric acid secretion, with an activity index of 0.15-0.3 for inhibiting gastric acid secretion. It also has low protein binding properties, which may result in drug interactions with other drugs or foods that have high protein binding properties.

• Brand: Biosynth

Chemical properties

• Molecular weight: 385.36 g/mol
• Formula: C₁₆H₁₄F₃N₃O₃S
• Purity: Min. 98 Area-%
• Color/Form: White Off-White Powder
• InChI: InChI=1S/C16H14F3N3O3S/c1-10-13(20-7-6-14(10)25-9-16(17,18)19)8-26(23,24)15-21-11-4-2-3-5-12(11)22-15/h2-7H,8-9H2,1H3,(H,21,22)
• InChI key: InChIKey=TVMJMCGRSSSSDJ-UHFFFAOYSA-N
• SMILES: Cc1c(OCC(F)(F)F)ccnc1CS(=O)(=O)c1nc2ccccc2[nH]1