Leupeptin hemisulphate salt monohydrate (Synthetic)

CAS: 55123-66-5

Ref. 3D-ILP-3851-PI

Product Information

• Name: Leupeptin hemisulphate salt monohydrate (Synthetic)
• Synonyms: N-Ac-LLR hemisulphate monohydrate, 6-O--D-Glucopyranosyl-D-glucopyranose, <span class="text-smallcaps">L</smallcap>-Leucinamide, N-acetyl-<smallcap>L</span>-leucyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-formylbutyl]-, <span class="text-smallcaps">L</smallcap>-Leucinamide, N-acetyl-<smallcap>L</span>-leucyl-N-[4-[(aminoiminomethyl)amino]-1-formylbutyl]-, (S)-, Ac-Leu-Leu-Arg-aldehyde . hemisulfate, Acetyl-<span class="text-smallcaps">L</smallcap>-leucyl-<smallcap>L</smallcap>-leucyl-<smallcap>L</span>-argininal, Leupeptin, N-Acetyl-<span class="text-smallcaps">L</smallcap>-leucyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-formylbutyl]-<smallcap>L</span>-leucinamide, N-acetyl-L-leucyl-L-leucyl-L-argininal

Description

Leupeptin is a naturally occurring protease inhibitor that has been synthetically produced for use as an experimental tool. Leupeptin inhibits the activity of basic proteins and enzymes by binding to them at the active site, preventing their access to substrate. This inhibition can be reversed with reducing agents (e.g., dithiothreitol). Leupeptin has been shown to inhibit neuronal death during anoxia in experimental models and has also been shown to have neurotrophic effects, which may be due to its ability to prevent protein aggregation.

• Brand: Biosynth

Chemical properties

• Molecular weight: 493.61 g/mol
• Formula: C₂₀H₃₈N₆O₄•(H₂SO₄)₀•H₂O
• Purity: Min. 95%