2-Methoxy-5-methyl-γ-phenylbenzenepropanol

CAS: 124937-73-1

Ref. 3D-IM145669

Product Information

• Name: 2-Methoxy-5-methyl-γ-phenylbenzenepropanol
• Synonyms: Tolterodine impurity A, 3-(2-Methoxy-5-Methylphenyl)-3-Phenylpropan-1-Ol, 3-(2-Methoxy-5-methylphenyl)-3-phenylpropanol, Benzenepropanol, 2-methoxy-5-methyl-γ-phenyl-

Description

2-Methoxy-5-methyl-gamma-phenylbenzenepropanol is a synthetic compound that is used as an intermediate in the synthesis of coumarin derivatives. Reaction with sulfonating agents produces sulfones, and reaction with borohydride reagents produces boronates. The synthesis of 2-methoxy-5-methyl-gamma-phenylbenzenepropanol can be accomplished by the reduction of diphenyl ethers with lithium aluminum hydride or borohydride. The reduction can also be carried out using lanthanum oxide and potassium borohydride. The reaction proceeds smoothly at room temperature in nonpolar solvents.
2-Methoxy-5-methyl-gamma-phenylbenzenepropanol reacts with chloride to produce the corresponding chlorides, which are useful intermediates for the synthesis of tolterodine tartrate, a drug used to treat urinary inc

• Brand: Biosynth

Chemical properties

• Molecular weight: 256.34 g/mol
• Formula: C₁₇H₂₀O₂
• Purity: Min. 95%
• InChI: InChI=1S/C17H20O2/c1-13-8-9-17(19-2)16(12-13)15(10-11-18)14-6-4-3-5-7-14/h3-9,12,15,18H,10-11H2,1-2H3
• InChI key: InChIKey=OCGTUTJXBDQGKL-UHFFFAOYSA-N
• SMILES: COc1ccc(C)cc1C(CCO)c1ccccc1