Methotrexate-5-monomethyl ester
CAS: 67022-39-3
Ref. 3D-IM71453
| 5mg | 154.00 € | ||
| 10mg | 208.00 € | ||
| 25mg | 379.00 € | ||
| 50mg | 482.00 € | ||
| 100mg | 780.00 € |
Product Information
- Methotrexate impurity H
Methotrexate-5-monomethyl ester is an analytical standard that is synthesized synthetically. The synthetic route used to produce the compound has been optimized for high purity, making this product suitable for use as a drug product or impurity standard. The structure of methotrexate-5-monomethyl ester was confirmed by 1H and 13C NMR spectroscopy and mass spectrometry. Methotrexate-5-monomethyl ester is an impurity found in the synthesis of methotrexate and is a metabolite of methotrexate. It has been shown to inhibit DNA synthesis and protein synthesis in animal cells, which may be due to its ability to inhibit transcription factors such as NFATc1, NFkB, STAT3, STAT5A and STAT5B.
Chemical properties
Technical inquiry about: 3D-IM71453 Methotrexate-5-monomethyl ester
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