LUF 5834

CAS: 333962-91-7

Ref. 3D-INA96291

Product Information

• Name: LUF 5834
• Brand: Biosynth
• Description: LUF 5834 is a novel adenosine A1 receptor agonist that has been shown to have significant efficacy in vivo against inflammatory diseases. It was found to be a potent and selective agonist of the A1 receptor in vitro. LUF 5834 also had an allosteric modulating effect on the adenosine A3 receptor, which is involved in immune and inflammatory responses. LUF 5834 binds to both the adenosine A1 receptor and the A3 receptor with high affinity and selectivity, but does not bind to any other adenosine receptors at concentrations up to 10 μM. The binding site for LUF 5834 on the A1 receptor was determined by molecular modeling studies as well as binding experiments. These results suggest that LUF 5834 can be used for treating inflammatory diseases or other disorders involving inflammation.

Chemical properties

• Molecular weight: 348.38 g/mol
• Formula: C₁₇H₁₂N₆OS
• Purity: Min. 95%