Product Information
Beclabuvir is a novel antiviral drug that inhibits the enzyme human immunodeficiency virus (HIV) integrase. Beclabuvir has a long half-life, low toxicity, and high bioavailability in humans. The pharmacokinetic properties of beclabuvir are similar to those of other antiviral drugs, such as ritonavir, saquinavir, and indinavir. When beclabuvir is administered to patients with hepatic impairment, it accumulates in the plasma. Beclabuvir is metabolized by multiple pathways including oxidation by cytochrome P450 enzymes and conjugation with glucuronic acid. This drug also binds to the transporter protein P-glycoprotein and inhibits transporter activity in vitro. The binding affinity of beclabuvir was confirmed using an x-ray diffraction data analysis and molecular docking studies.
Chemical properties
Technical inquiry about: 3D-INB00233 Beclabuvir
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