Product Information
TAPI-1 is a protease inhibitor that inhibits the activity of three major enzymes: Collagenase, MMP, and Stromelysin. TAPI-1 has been shown to inhibit the activation of neurokinin-1 receptor (NK1R) in human lung cancer cell lines. TAPI-1 also blocks the activity of epidermal growth factor (EGF) by inhibiting its binding to its receptor, which may be a potential treatment for autoimmune diseases. TAPI-1 inhibits the production of inflammatory cytokines and chemokines in human lung carcinoma cells. Furthermore, TAPI-1 blocks tumorigenesis in animal models of colon cancer and breast cancer by inducing apoptosis.
Chemical properties
Technical inquiry about: 3D-INH-3855-PI TAPI-1
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