Olanzapine N-oxide

CAS: 174794-02-6

Ref. 3D-IO106348

Product Information

• Name: Olanzapine N-oxide
• Synonyms: Olanzapine impurity 4Olanzapine impurity D
• Brand: Biosynth
• Description: Olanzapine N-oxide is a metabolite of olanzapine. It is produced by the oxidative deamination of olanzapine, which is catalyzed by cytochrome P450 enzymes. Olanzapine N-oxide has been shown to be responsible for some of the side effects associated with olanzapine, such as weight gain and sedation. The presence of olanzapine N-oxide in human plasma has been shown to increase with age and in women, which may be due to its higher affinity for α1-acid glycoprotein. Olanzapine N-oxide can be detected in urine or faeces using gas chromatography/mass spectrometry (GC/MS) or liquid chromatography with tandem mass spectrometry (LC/MS).

Chemical properties

• Molecular weight: 328.43 g/mol
• Formula: C₁₇H₂₀N₄OS
• Purity: Min. 95%
• Color/Form: Powder