15-O-Demethyl Tacrolimus

CAS: 151039-41-7

Ref. 3D-IO167490

Product Information

• Name: 15-O-Demethyl Tacrolimus
• Brand: Biosynth
• Description: Tacrolimus is a macrolide that is used as an immunosuppressive drug. It has been shown to bind to the FK-binding protein, which in turn inhibits calcineurin. This prevents the release of IL-2, TNF-α and other cytokines. The immunosuppressive effects of tacrolimus have been evaluated using analytical methods such as coefficients, affinity, and monitoring techniques such as immunoassays and agglutination. These techniques are used to evaluate the plasma concentration of tacrolimus. Tacrolimus also binds to proteins in the blood samples and can be detected by turbidimetric or electrochemiluminescence immunoassay reagents.

Chemical properties

• Molecular weight: 789.99 g/mol
• Formula: C₄₃H₆₇NO₁₂
• Purity: Min. 95%