(1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline

CAS: 118864-75-8

Ref. 3D-IP14817

Product Information

• Name: (1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline
• Synonyms: Solifenacin impurity A, (+)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline, (1R)-1-phenyl-1,2,3,4-tetrahydroisoquinoline, (1S)-1,2,3,4-Tetrahydro-1-(phenyl-d5)isoquinoline, (1S)-1,2,3,4-Tetrahydro-1-phenylisoquinoline, (S)-1,2,3,4-Tetrahydro-1-Phenylisoquinoline, (S)-1-(Phenyl-d5)-1,2,3,4-tetrahydroisoquinoline, (S)-1-1-Phenyl-1,2,3,4-Tetrahy, (S)-1-Phenyl-1,2,3,4-Trtrohydroisoquinoline, (S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline, Isoquinoline, 1,2,3,4-tetrahydro-1-phenyl-, (1S)-, Isoquinoline, 1,2,3,4-tetrahydro-1-phenyl-, (S)-, Solifenacin(YM905) intermediate 10

Description

(1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline is a drug used to treat depression. It is an antidepressant drug that inhibits the reuptake of serotonin and norepinephrine in the brain by blocking their transport into the nerve cells. The drug acts as a weak inhibitor of monoamine oxidase (MAO). It also has an effect on bladder function. This compound is synthesized from 1-phenyl-2,5-dihydrothiazole by way of a sequence of reactions that includes the formation of an amine salt via reaction with phosphorus pentoxide and chloroacetic acid followed by conversion to the chloride with thionyl chloride.

• Brand: Biosynth

Chemical properties

• Molecular weight: 209.29 g/mol
• Formula: C₁₅H₁₅N
• Purity: Min. 95%
• Color/Form: White Powder