Roflumilast Impurity A

CAS: 475271-62-6

Ref. 3D-IR168438

Product Information

• Name: Roflumilast Impurity A
• Synonyms: 3-(Cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-hydroxybenzamide
• Brand: Biosynth
• Description: Roflumilast impurity A is a metabolite of roflumilast. It is a drug product that is used as an analytical standard for the determination of roflumilast in HPLC analysis. Roflumilast impurity A is not natural and is synthetic. It has been shown to be a substrate for CYP1A2, CYP2C8, CYP2C9, and CYP3A4 enzymes. Studies have shown that it may be involved in the metabolism of roflumilast through hydroxylation and deamination.

Chemical properties

• Molecular weight: 353.2 g/mol
• Formula: C₁₆H₁₄Cl₂N₂O₃
• Purity: Min. 95%