Simvastatin hydroxy acid methyl ester

CAS: 145576-26-7

Ref. 3D-IS27837

Product Information

• Name: Simvastatin hydroxy acid methyl ester
• Synonyms: ( ?R,?R,1S,2S,6R,8S,8aR)-8-(2,2-Dimethyl-1-oxobutoxy)-1,2,6,7,8,8a-hexahydro - ?,?-dihydroxy-2,6-dimethyl-1-naphthaleneheptanoic Aci d Methyl Ester
• Brand: Biosynth
• Description: Simvastatin hydroxy acid methyl ester is a drug product that belongs to the group of statins. It is an impurity standard for synthetic simvastatin as well as a natural metabolite formed from simvastatin through oxidation and hydroxylation. This impurity is used in analytical and pharmacopoeia testing for simvastatin, and has been shown to inhibit the production of cholesterol by blocking the synthesis of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR).

Chemical properties

• Molecular weight: 450.61 g/mol
• Formula: C₂₆H₄₂O₆
• Purity: Min. 95%