Product Information
Name:Triphenylmethanol
Synonyms:
- a,a-DiphenylbenzenemethanolZidovudine Impurity DHydroxytriphenylmethaneBL 3756
Brand:Biosynth
Description:Triphenylmethanol (TPM) is an inhibitor of the enzyme alcohol dehydrogenase. It is synthesized by reacting p-hydroxybenzoic acid with a hydroxyl group in the presence of trifluoroacetic acid and potassium carbonate. The reaction solution was then analyzed by x-ray crystallography, revealing the molecular structure of TPM. TPM binds to the metal ion in a hydroxyl group, preventing alcohol dehydrogenase from oxidizing ethanol to acetaldehyde. This mechanism also explains why TPM inhibits other enzymes that use this same metal ion cofactor such as carboxypeptidase A and aminopeptidase P, which are involved in protein synthesis and degradation.
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Chemical properties
Molecular weight:260.33 g/mol
Formula:C19H16O
Purity:Min. 95%
Color/Form:White Beige Slightly Yellow Powder
InChI:InChI=1S/C19H16O/c20-19(16-10-4-1-5-11-16,17-12-6-2-7-13-17)18-14-8-3-9-15-18/h1-15,20H
InChI key:InChIKey=LZTRCELOJRDYMQ-UHFFFAOYSA-N
SMILES:OC(c1ccccc1)(c1ccccc1)c1ccccc1
Technical inquiry about: Triphenylmethanol
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