6-Ethynyl-2-methylquinoline

CAS: 1233505-71-9

Ref. 3D-IZB50571

Product Information

• Name: 6-Ethynyl-2-methylquinoline
• Brand: Biosynth
• Description: 6-Ethynyl-2-methylquinoline is a natural product that can be synthesized by the photochemical reaction of arylacetylenes with styrenes. The synthesis proceeds via an anti-markovnikov cyclization to yield the desired product. This process requires two steps and produces two products, one being 6-ethynyl-2-methylquinoline. Protodeboronation then takes place on the methyl group to yield 6-ethynylquinoline. Mechanistic studies have shown that this reaction is catalytic, with regioselectivity controlled by the protodeboronation step.

Chemical properties

• Molecular weight: 167.21 g/mol
• Formula: C₁₂H₉N
• Purity: Min. 95%