ELR510444
CAS:
Ref. 3D-IZB94835
1g
1,952.00€
2g
2,951.00€
100mg
926.00€
250mg
1,248.00€
500mg
1,408.00€
Product Information
Name:ELR510444
Brand:Biosynth
Description:ELR510444 is a small molecule that inhibits the expression of survivin, an apoptosis protein. ELR510444 has potent antitumor activity and is currently being evaluated in clinical trials for the treatment of cervical cancer and renal cell cancer. This drug is being developed by Eli Lilly and Company. ELR510444 also has antiangiogenic properties, which may be due to its ability to inhibit tumor growth by blocking the growth factor VEGF signaling pathway. The mechanism of action of ELR510444 is still under investigation, but it has been shown to bind to the drug transporter ABCG2 and inhibit cellular proliferation in vitro.
ELR510444 was docked against a number of proteins implicated in cancer progression including EGFR, HER2, MET, PIK3CA, and AKT1 using molecular docking analysis. It was found that ELR510444 binds to these proteins with high affinity (Kd = 0.6-0.7 nM) and
ELR510444 was docked against a number of proteins implicated in cancer progression including EGFR, HER2, MET, PIK3CA, and AKT1 using molecular docking analysis. It was found that ELR510444 binds to these proteins with high affinity (Kd = 0.6-0.7 nM) and
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:368.47 g/mol
Formula:C19H16N2O2S2
Purity:Min. 95%
Technical inquiry about: ELR510444
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