3-Isobutyl-1-methylxanthine

CAS: 28822-58-4

Ref. 3D-J-640140

Product Information

• Name: 3-Isobutyl-1-methylxanthine
• Synonyms: 1-Methyl-3-isobutylxanthine, 3,7-Dihydro-1-methyl-3-(2-methylpropyl)-1H-purine-2,6-dione, 3-Isobutyl-1-methyl-2,6(1H,3H)-purinedione, 1-Methyl-3-(2-methylpropyl)-2,3,6,9-tetrahydro-1H-purine-2,6-dione, 1H-Purine-2,6-dione, 3,9-dihydro-1-methyl-3-(2-methylpropyl)-, 3,7-Dihydro-3-isobutyl-1-methyl-1H-purin-2,6-dion, 3,7-dihidro-3-isobutil-1-metil-1H-purina-2,6-diona, 3,7-dihydro-3-isobutyl-1-methyl-1H-purine-2,6-dione, 3,9-Dihydro-1-methyl-3-(2-methylpropyl)-1H-purine-2,6-dione, 3-Isobutyl-1-methyl-1H-purine-2,6(3H,7H)-dione, 3-Isobutyl-1-methyl-3,7-dihydro-1H-purine-2,6-dione, IMX, Ibmx, Isobutylmethylxanthine, Methylisobutylxanthine, Nsc 165960, Sc 2964, Xanthine, 3-isobutyl-1-methyl-, 1H-Purine-2,6-dione, 3,7-dihydro-1-methyl-3-(2-methylpropyl)-

Description

A non-specific inhibitor of cAMP and cGMP phosphodiesterases (PDEs) with IC50 values between 2 and 50 µM. 2-isobutyl-1-methylxanthine (IBMX) has also been found to inhibit phenylephrine-induced 5-HT release by neuroendocrine epithelial cells and IBMX-mediated increase in cAMP and upregulation of Ca2+ channels promotes neuronal differentiation. Additionally IBMX stimulates secretion of thyroid hormones, resulting in cAMP-mediated activation of glycogenolysis and reduced glycogen storage.

• Brand: Biosynth

Chemical properties

• Molecular weight: 222.24 g/mol
• Formula: C₁₀H₁₄N₄O₂