Product Information
- Acethropan
- Acortan
- Acorto
- Acth
- Acthar
- Acthormone
- Acton
- Acton (hormone)
- Actonar
- Adrenal cortex hormone
- See more synonyms
- Adrenocorticotrophic hormone
- Adrenocorticotrophin
- Adrenocorticotropic hormone
- Adrenocorticotropin
- Adrenocorticotropin hormone
- Adrenomone
- Adrenotrophin
- Alfatrofin
- Chorionic corticotropin
- Cibacthen
- Corstiline
- Corticotrophin
- Corticotrophine
- Corticotropin-like substances
- Corticotropina
- Cortiphyson
- Cortrophimn
- Cortrophin
- Duracton
- Dynamone
- Exacthin
- Humactid
- Isactid
- Nuvacthen
- ProActon
- Reacthin
- Solacthyl
- Tubex
Corticotropin is a peptide hormone that is produced by the anterior lobe of the pituitary gland in response to stress or injury. It is used as an immunosuppressant and anti-inflammatory agent. Corticotropin binds to corticotropin receptors on cells, which triggers a series of reactions that lead to inflammation and cell death. Corticotropin has been shown to inhibit ion channels, such as voltage-gated sodium channels and calcium channels, which are responsible for signaling the release of neurotransmitters. Corticotropin also inhibits ligand-gated ion channels, such as NMDA receptors and GABA receptors, which regulate neuronal excitability.
Chemical properties
Technical inquiry about: 3D-JAA00260 Corticotropin
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