DNA ligase (ATP)

CAS: 9015-85-4

Ref. 3D-JAA01585

Product Information

• Name: DNA ligase (ATP)
• Synonyms: 9⁰N DNA Ligase, 9⁰N ligase, 9N DNA Ligase, ATP-dependent DNA ligase, CircLigase, CircLigase I, CircLigase II, DNA joinase, DNA ligase, DNA ligase 1, DNA ligase I, DNA-joining enzyme, Deoxyribonucleate ligase, Deoxyribonucleic acid joinase, Deoxyribonucleic acid ligase, Deoxyribonucleic joinase, Deoxyribonucleic ligase, Deoxyribonucleic-joining enzyme, E.C. 6.5.1.1, Ec 6.5.1.1, NHR ligase, Nucleotide ligase, PBCV-1 ligase, Pfu DNA Ligase, Polydeoxyribonucleotide (adenosine triphosphate) synthetase, Polynucleotide ligase, Polynucleotide synthetase, Polynucleotide synthetase (ATP), Sealase, Single-stranded DNA cyclase, Single-stranded DNA ligase, Sintetasa, Polidesoxirribonucleotido, SplintR ligase, Synthetase, Polydeoxyribonucleotid, Synthetase, Polydesoxyribonucleotide, Synthetase, polydeoxyribonucleotide, T3 DNA ligase, T4 DNA ligase, T4 polynucleotide ligase, T7 DNA ligase, Taq DNA ligase, Thermophage DNA ligase, Synthetase, polydeoxyribonucleotide (adenosine triphosphate)

Description

DNA ligase (ATP) is an enzyme that plays a crucial role in DNA replication and repair. It catalyzes the formation of phosphodiester bonds between adjacent nucleotides, sealing the gaps in the DNA strand. This enzyme has been shown to be involved in various cellular processes such as apoptosis, protein kinase activity, and cancer cell growth. Studies have revealed that inhibitors of this enzyme have potential anticancer properties and can be used as tumor inhibitors. Capsaicin analogs have been identified as potent inhibitors of DNA ligase (ATP), which may help in developing novel anticancer therapies. Urine from Chinese patients with bladder cancer has also been found to contain elevated levels of this enzyme, making it a potential biomarker for cancer diagnosis and treatment monitoring.

• Brand: Biosynth

Chemical properties

• Molecular weight: 0 g/mol