Pyroglutamate aminopeptidase from pyrococcus furiosus, recombinant from E. coli
CAS: 9075-21-2
Ref. 3D-JAA07521
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Product Information
- Pyroglutamate aminopeptidase I
- E.C. 3.4.11.8
- Pyrrolidonyl peptidase
- Aminopeptidase, pyroglutamate
- Pyroglutamate Aminopeptidase from E. coli
- Pyrrolidonecarboxylate peptidase
Pyroglutamate aminopeptidase from Pyrococcus furiosus is a recombinant protein produced in E. coli. It is an analog of the natural enzyme and can be used as a tool for studying its activity and inhibition. This enzyme has been shown to play a role in apoptosis and cell cycle regulation, making it a potential target for cancer therapy. Inhibitors of pyroglutamate aminopeptidase have been developed as medicinal compounds with anti-tumor properties, showing selective cytotoxicity towards cancer cells over normal human cells. The use of this enzyme as an inhibitor of protein kinases involved in the regulation of the cell cycle makes it an attractive target for the development of novel cancer therapies.
Chemical properties
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