(4-Chlorophenyl)[4-(trifluoromethyl)phenyl]methanone

CAS: 34328-31-9

Ref. 3D-JBA32831

Product Information

• Name: (4-Chlorophenyl)[4-(trifluoromethyl)phenyl]methanone
• Brand: Biosynth
• Description: 4-Chlorophenyl-[4-(trifluoromethyl)phenyl]methanone (TFMPP) is a psychostimulant drug that binds to the serotonin 5-HT2A receptor. TFMPP has been shown to produce effects in wild-type mice similar to those of amphetamine, but not in mice with the 5-HT2A receptor gene knocked out. The effective dose for TFMPP was determined by measuring the effect on extracellular dopamine levels in rat striatal tissue. TFMPP also inhibits the activity of an enzyme called adenosine deaminase, which breaks down endogenous adenosine. This inhibition leads to increased concentrations of adenosine and allosteric modulator binding at the 5-HT2A receptor site. TFMPP has also been shown to bind to a site on the G protein called Gαi3 and stabilize it, which may explain its ability to inhibit adenosine de

Chemical properties

• Molecular weight: 284.66 g/mol
• Formula: C₁₄H₈ClF₃O
• Purity: Min. 95%