15(S)-HETE-d8

CAS: 84807-87-4

Ref. 3D-JDA80787

Product Information

• Name: 15(S)-HETE-d8
• Brand: Biosynth
• Description: 15(S)-HETE-d8 is an activated form of 15-hydroxyeicosatetraenoic acid (15(S)-HETE) produced by the enzyme 15-lipoxygenase. It is a member of the eicosanoid class of fatty acids and has been shown to be involved in tissue inflammation, adipose tissue, and regulation of prostaglandin production. The 15(S)-HETE-d8 profile has been shown to be resistant to the efflux transporter P-glycoprotein, which may be due to its hydrophobic properties. This compound has also been shown to inhibit toll-like receptor 4 signaling and induce IL-10 release from macrophages in a dose dependent manner.

Chemical properties

• Molecular weight: 328.5 g/mol
• Formula: C₂₀H₃₂O₃
• Purity: Min. 95%