Product Information
FT827 is a small molecule that is a covalent inhibitor of ubiquitin ligases. FT827 inhibits the activity of the proteasome by inhibiting ubiquitin ligases and proteasome-dependent protein degradation. FT827 has been shown to inhibit cancer growth in organoids, as well as infection by Borrelia burgdorferi, an agent of Lyme disease. FT827 was also shown to inhibit the replication of rabies virus in vitro. The precise molecular mechanism of action for this drug remains unknown, but it may be due to its ability to inhibit ubiquitin ligases.
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Chemical properties
Technical inquiry about: 3D-JDD53786 FT827
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