23-Hydroxybudesonide

Ref. 3D-JEA42303

Product Information

• Name: 23-Hydroxybudesonide
• Brand: Biosynth
• Description: 23-Hydroxybudesonide is a synthetic, inactive metabolite of budesonide. It is formed by the liver cells and has been found to be a potent inhibitor of human eosinophilic leukemia cell growth in culture. 23-Hydoxybudesonide also inhibits the proliferation of colonic epithelial cells in vitro. 23-Hydroxybudesonide has minimal activity when given orally, but it can be administered nasally without any significant side effects. The metabolism of this drug is mediated by cytochrome P450 3A5 (CYP3A5).

Chemical properties

• Molecular weight: 446.5 g/mol
• Formula: C₂₅H₃₄O₇
• Purity: Min. 95%