Product Information
- 4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-2-pyridinecarboxamide
- BAY 43-9007
- 2-Pyridinecarboxamide, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-
- N-Desmethylsorafenib
- N-[4-Chloro-3-(trifluoromethyl)phenyl]-N′-[4-(2-carbamoyl-4-pyridyloxy)phenyl]urea
N-desmethyl sorafenib is an analytical standard for the HPLC assay of sorafenib. It is a metabolite of sorafenib, which is a drug used in the treatment of cancer. It has been shown to inhibit protein synthesis and cell growth in vitro and in vivo. N-desmethyl sorafenib has been shown to inhibit the activity of methionine adenosyltransferase, leading to inhibition of DNA synthesis. The chemical properties are similar to those of other drugs that have been approved by the US Food and Drug Administration.
Chemical properties
Technical inquiry about: 3D-JLA46174 N-Desmethyl sorafenib
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