Product Information
TC-E 5005 is a potent, selective inhibitor of the multidrug resistance-associated protein (MRP). It is used to study MRP-mediated drug transport in tissues and to develop new anti-cancer drugs. TC-E 5005 has been shown to inhibit phenylephrine-induced contraction of rat bladder strips. This agent also inhibits hydroxylation of noradrenaline, which may play a role in the development of glioblastoma cells. TC-E 5005 is an analog of phenoxybenzamine and structurally related to other drugs that inhibit the action of prostaglandins, such as papaverine.
Chemical properties
Technical inquiry about: 3D-JNB70564 TC-E 5005
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