Product Information
- 1-(1-Piperidinyl)-2-propen-1-one
- 1-(2-Propenoyl)piperidine
- 1-Acryloylpiperidine
- 2-Propen-1-One, 1-(1-Piperidinyl)-
- N-Acryloylpiperidine
- N-Pentamethyleneacrylamide
- Piperidine, 1-(1-oxo-2-propenyl)-
- Piperidine, 1-acryloyl-
1-(Piperidin-1-yl)prop-2-en-1-one is a heterocycle that is used as a pharmaceutical compound. It is one of the most potent known inhibitors of cellular efflux pumps, which are responsible for recycling natural products and xenobiotics from cells. The inhibition of these pumps by 1-(piperidin-1-yl)prop-2-en-1-one leads to increased concentrations of estrogens in the blood plasma, which has been shown to lead to an increase in breast cancer cell growth. 1-(Piperidin-1-yl)prop-2-en-1-one also inhibits aromatase, an enzyme that converts androgens into estrogens. This can lead to suppression of estrogen levels in males and females. The drug also has depressant activity and is used for treating anxiety disorders.
Chemical properties
Technical inquiry about: 3D-KAA04337 1-(Piperidin-1-yl)prop-2-en-1-one
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