Product Information
- Morpholine, 4- (phenylmethyl)-
4-Benzylmorpholine is a solvent that is used in organic chemistry as a reactant and as a chemical intermediate. It has been shown to inhibit the activity of cytochrome P450 enzymes in human liver microsomes, which are enzymes that metabolize xenobiotics. 4-Benzylmorpholine binds to the heme moiety of these enzymes, preventing them from carrying out their function. This inhibition of p-450 enzymes leads to an increase in the levels of reactive oxygen species and lipid peroxidation, which may be responsible for its toxicity. The binding site for 4-benzylmorpholine on p-450 enzymes has been identified using kinetic analysis and NMR spectroscopy as a hydrogen bond between the amine group and the hydroxyl group at C3 on the ring.
Chemical properties
Technical inquiry about: 3D-KAA31600 4-Benzylmorpholine
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