Pifithrin-±, p-Nitro, Cyclic

Ref. 3D-KCA47738

Product Information

• Name: Pifithrin-±, p-Nitro, Cyclic
• Brand: Biosynth
• Description: Pifithrin-± is a phosphatase inhibitor that has been shown to inhibit the phosphatase activity of the human liver. It also has an anti-cancer effect and is used for diagnostic purposes in the localization of cancer cells. Pifithrin-± binds to the p-nitrophenyl phosphate and inhibits its activity, leading to a decrease in cyclic adenosine monophosphate (cAMP) levels in proximal tubules. This inhibition causes a decrease in uptake of ions, including calcium ions, which leads to increased calcium ion concentrations in urine. Pifithrin-± also inhibits protein synthesis by blocking the ryanodine receptor and also blocks cell growth by binding to the apical membrane on cells.END>>

Chemical properties

• Molecular weight: 299.35 g/mol
• Formula: C₁₅H₁₃N₃O₂S
• Purity: Min. 95%