3-Chloro-N-methyl-2-nitroaniline

CAS: 60498-57-9

Ref. 3D-KCA49857

Product Information

• Name: 3-Chloro-N-methyl-2-nitroaniline
• Brand: Biosynth
• Description: 3-Chloro-N-methyl-2-nitroaniline is an antibiotic that belongs to the group of quinolone antibiotics. It has a broad spectrum against Gram-positive and Gram-negative bacteria, including methicillin resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa. 3-Chloro-N-methyl-2-nitroaniline binds to bacterial DNA gyrase and topoisomerase IV, as well as human DNA gyrase and topoisomerase II, inhibiting their activity. This leads to cell death by interfering with the production of proteins vital for cell division. The optimal parameters for this drug have been found using isothermal titration calorimetry on the enzyme gyrase in the presence of different concentrations of 3CMA. Pharmacological targets for this drug include DNA gyrase and topoisomerase IV.

Chemical properties

• Molecular weight: 186.59 g/mol
• Formula: C₇H₇ClN₂O₂
• Purity: Min. 95%