Product Information
Name:PD166326
Brand:Biosynth
Description:PD166326 is a protein data inhibitor drug that is used to inhibit the bcr-abl kinase, which is responsible for the uncontrolled proliferation of cells in cancer. PD166326 has been shown to inhibit the kinase activity of bcr-abl and increase mitochondrial membrane potential, leading to cell death by apoptosis. The compound has also been shown to inhibit the growth of skin cancer cells in mice. PD166326 binds to an active site on bcr-abl and blocks its ATP binding site, preventing phosphorylation of downstream substrates such as paxillin and caspase 3, which are involved in cell proliferation. This drug has also been shown to be effective against myelogenous leukemia cells in mice.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:427.28 g/mol
Formula:C21H16Cl2N4O2
Purity:Min. 95%
Technical inquiry about: PD166326
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