Protein 4E-BP1 (initiation factor eIF-4-binding protein 1) (human)
CAS: 185703-54-2
Ref. 3D-KHA70354
| 1mg | To inquire |
Product Information
Protein 4E-BP1 is a protein that binds to the eIF4E initiation factor and regulates the translation of mRNA. It has been shown to be involved in cancer, as well as other diseases. Protein 4E-BP1 has been shown to regulate the translation of mRNA by binding to the eIF4E initiation factor, which is required for translation in cells. Protein 4E-BP1 is also involved in autophagy, which is a process of self-degradation that cells use to destroy damaged or unnecessary cellular components. The level of this protein can be used as a diagnostic marker for cancer, and it has been found at high levels in T-cell lymphomas. This protein is phosphorylated at serine 40 and serine 46 in response to physiological levels of growth factors such as insulin or IGF-1. Phosphorylation at these sites blocks the ability of 4E-BP1 to bind with eIF4E and inhibit translation. When phosph
Chemical properties
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