Product Information
GDC-0077 is a small molecule that specifically targets the lipid kinase activity of CDK4/6. It has been shown to have anti-inflammatory effects in animal models of inflammatory diseases, such as arthritis and colitis, by suppressing the expression of inflammatory genes. GDC-0077 has also been shown to be effective in suppressing tumor growth and prolonging survival in animal models of cancer. GDC-0077 inhibits the proliferation of cancer cells by interrupting cell cycle progression at the G2/M checkpoint. The compound is being investigated for its potential as a treatment for cancers with mutations in CDK4 or CDK6, such as breast, prostate, and endometrial cancers.
Chemical properties
Technical inquiry about: 3D-KHD57102 GDC-0077
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