iRucaparib-AP6
CAS: 2410557-00-3
Ref. 3D-KWD55700
| 1mg | To inquire | ||
| 5mg | To inquire | ||
| 10mg | To inquire | ||
| 25mg | To inquire | ||
| 50mg | To inquire |
Product Information
iRucaparib-AP6 is a small molecule that belongs to the group of ubiquitin ligases. It inhibits the ubiquitin ligase activity of human Poly (ADP-ribose) polymerase 1 (PARP1) and PARP2, which are enzymes involved in DNA repair. iRucaparib-AP6 has been shown to inhibit tumor growth by inducing necrotic cell death. This drug also blocks the activation of PARP1 and PARP2, which in turn prevents the production of adenosine diphosphate ribose (ADPR). The homologous recombination process is blocked by this inhibition and leads to a paradigm shift in cancer treatment.
Chemical properties
Technical inquiry about: 3D-KWD55700 iRucaparib-AP6
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