Product Information
- Bengal Rose
- HFinCl<sub>4</sub>I<sub>4</sub>
- Rb 1017
- Rose Bengale
- SODIUM TETRAIODODICHLOROFLUORESCEIN
- C.I. Acid Red 94
- redno.105
- Rose Bengal
- TETRACHLOROTETRAIODOFLUORESCEIN SODIUM SALT
- RB
- See more synonyms
- rose
- C.I.AcidRed94(45440)
- TETRAIODOTETRACHLOROFLUORESCEIN DISODIUM SALT
- 2,3,4,5-tetrachloro-6-(6-hydroxy-2,4,5,7-tetraiodo-3-oxo-3H-xanthen-9-yl)benzoic acid
- HFinCl4I4
PV-10 is a peptide that activates ion channels. It is an agonist for the nicotinic acetylcholine receptor (nAChR) and a low-affinity antagonist for the N-methyl-D-aspartate receptor (NMDAR). PV-10 binds to specific sites on the nAChR, which causes the channel to open and allow ions to flow into the cell. This leads to depolarization of the membrane, which triggers an action potential in neurons. PV-10 is also able to bind to other proteins such as NR1 subunits of NMDARs and alpha 7 subunits of nAChRs. These interactions inhibit the function of these receptors and prevent them from opening their channels. This prevents calcium influx into cells, blocking neurotransmitter release and preventing the activation of downstream pathways that lead to neuronal death. PV-10 has been shown to be selective for certain types of ion channels over others
Chemical properties
Technical inquiry about: 3D-LAA12148 PV-10
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