Amphotericin B methyl ester
CAS: 36148-89-7
Ref. 3D-LBA14889
2mg | 480.00 € | ||
5mg | 880.00 € | ||
10mg | 1,274.00 € | ||
25mg | 2,449.00 € |
Product Information
- 14,39-Dioxabicyclo[33.3.1]nonatriacontane, amphotericin B deriv.
- Amphotericin B monomethyl ester
- Amphotericin B, methyl ester
- Methylamphotericin B
- methyl (1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19Z,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-[(3-amino-3,6-dideoxy-β-D-mannopyranosyl)oxy]-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylate hydrochloride
- methyl (1R,3S,5S,8S,9S,11R,15S,16S,17R,18S,25Z,33R,35S,36R,37S)-33-[(3-amino-3,6-dideoxy-β-D-mannopyranosyl)oxy]-1,3,5,8,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylate
Amphotericin B is an antifungal agent that belongs to a class of polyenes. It binds to ergosterol in fungal cell membranes and alters their permeability, thereby causing leakage of cellular contents. Amphotericin B methyl ester is a water-soluble prodrug form of amphotericin B that has been shown to have anti-infective activity against many types of fungi, including Candida albicans, Trichosporon beigelii, and Aspergillus fumigatus. Amphotericin B methyl ester has also been shown to be effective against some bacteria such as Streptococcus pneumoniae, Haemophilus influenzae, and Mycoplasma pneumoniae. In vitro studies have demonstrated the detection sensitivity of amphotericin B methyl ester for Coccidioides immitis at 1 ng/ml or less. Amphotericin B methyl ester does not exhibit any hemolytic activity even at concentrations
Chemical properties
Technical inquiry about: 3D-LBA14889 Amphotericin B methyl ester
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