Product Information
GNE-272 is a small molecule that binds to the bromodomain of a protein and inhibits the function of this protein. It has been shown to have neuroprotective effects in vitro and in vivo, as well as anti-inflammatory effects. GNE-272 has also been shown to prevent cancer cell growth by inhibiting the activation of proteins involved in cell survival. The mechanism for this inhibition is not yet known, but it may be due to its ability to inhibit the expression of marker proteins that are linked with cancer cells and their growth. GNE-272 has also been shown to be active against urinary infections caused by E. coli and Staphylococcus aureus, as well as influenza virus in vitro. This drug also has activity against other viruses such as West Nile virus, herpes simplex virus type 1, and human cytomegalovirus. GNE-272 binds to histone H3, which is important for cellular physiology and cell culture.
Chemical properties
Technical inquiry about: 3D-LCD42893 GNE-272
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