Product Information
YKL-05-099 is a small molecule that inhibits the activity of histone acetyltransferases and histone deacetylases. Histones are proteins involved in DNA packaging, which are important for the transcriptional regulation of genes. YKL-05-099 has been shown to inhibit leukemia cells by inhibiting the anabolic effect of all-trans retinoic acid. YKL-05-099 also modulates cellular localization, affecting the migration of hematopoietic cells to bone marrow and their proliferation. The molecule has been shown to have pharmacokinetic properties that allow it to be administered orally. It is currently being studied as a potential treatment for myelodysplastic syndrome, a condition caused by abnormal hematopoietic cells in bone marrow.
Chemical properties
Technical inquiry about: 3D-LCD52965 YKL-05-099
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