Product Information
BSJ-03-123 is a ubiquitin ligase inhibitor that inhibits the ubiquitin-proteasome system. It has been shown to be effective in the treatment of leukemia cells and other cancers, such as prostate cancer. BSJ-03-123 inhibits the degradation of proteins by the proteasome, which leads to an accumulation of ubiquitinated proteins and cell death. This drug is not cytotoxic to normal cells, but it does cause apoptosis in cancer cells. The mechanism of action of BSJ-03-123 involves inhibition of the degraders that degrade ubiquitinated proteins and profiling studies have shown that its hydroxyl group may be responsible for this activity.
Chemical properties
Technical inquiry about: 3D-LUD49316 BSJ-03-123
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